Description

Palmitoyl Coenzyme A Potassium Salt is a high-purity, biologically active derivative of coenzyme A, essential for lipid metabolism research and enzymatic studies. This critical biochemical reagent serves as a specific substrate for enzymes involved in fatty acid synthesis, oxidation, and protein acylation. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for metabolic pathway analysis, enzyme kinetics, and the development of diagnostic assays.

Application

• Enzymology Research: As a key substrate for studying acyl-CoA synthetases, acyl-CoA dehydrogenases, and carnitine palmitoyltransferases (CPT-I & CPT-II).
• Lipid Metabolism Studies: Investigating β-oxidation pathways, fatty acid synthesis, and mitochondrial function in metabolic disease models.
• Protein Palmitoylation: Used in in vitro assays to study post-translational modification of proteins, crucial for cell signaling and membrane localization.
• Diagnostic Kit Development: A vital component in the formulation of clinical diagnostic kits for measuring specific enzyme activities related to metabolic disorders.
• Biochemical Assay Standard: Serves as a reference standard in HPLC and spectrophotometric assays for quantifying enzyme activity and substrate specificity.
• Pharmaceutical Screening: Employed in high-throughput screening (HTS) platforms to identify potential inhibitors or activators of lipid-metabolizing enzymes for drug discovery.

Basic Information

Product Name	Palmitoyl Coenzyme A Potassium Salt
CAS No.	1763-10-6
Molecular Formula	C37H64N7O17P3S • xK
Molecular Weight	Approx. 1057.3 (Free acid) + counterion
Synonyms	Palmitoyl-CoA Potassium Salt; Hexadecanoyl-CoA K+ Salt; Palmitoyl CoA K Salt; Coenzyme A, S-hexadecanoate, potassium salt; Palmitoyl-Coenzyme A K+; Palmityl-CoA Potassium; 3'-Phosphoadenosine 5'-(3-[(3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-{[3-oxo-3-({2-[(1-oxohexadecyl)thio]ethyl})amino]propyl}amino]butyl) dihydrogen diphosphate potassium salt
EINECS	217-178-5

Quality Control

Our Palmitoyl Coenzyme A Potassium Salt is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high biological activity. Each lot is characterized by multiple analytical techniques including HPLC for purity and enzymatic activity assays to confirm functional performance. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment. Our quality management system supports compliance with relevant standards for research and in vitro diagnostic use.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Aliquot into single-use vials to avoid repeated freeze-thaw cycles and maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder or lyophilized solid
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Assay (Enzymatic)	≥ 90% of theoretical activity
Water Content (KF)	≤ 5.0 %
Solubility	Soluble in water (clear, colorless to faint yellow solution)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.