Description

Oleoyl Coenzyme A is a critical biochemical intermediate, specifically a long-chain fatty acyl-CoA ester, essential for lipid metabolism. Its primary value lies in its role as a key substrate for studying and manipulating enzymatic processes in fatty acid oxidation, biosynthesis, and protein acylation. This high-purity compound is indispensable for researchers and manufacturers in pharmaceutical development, metabolic research, and diagnostic enzyme assay production.

Application

• Biochemical Research: Essential substrate for in vitro studies of enzymes like acyl-CoA dehydrogenases, thioesterases, and carnitine palmitoyltransferases (CPT1/CPT2).
• Drug Discovery & Development: Used in high-throughput screening (HTS) assays to identify modulators of metabolic pathways relevant to obesity, diabetes, and cancer.
• Diagnostic Kit Manufacturing: Serves as a key reagent in clinical diagnostic kits for measuring specific enzyme activities in patient samples.
• Metabolomics & Lipidomics: Used as a standard for the identification and quantification of acyl-CoA species in complex biological samples via LC-MS/MS.
• Enzyme Characterization: Critical for determining kinetic parameters (Km, Vmax) and inhibition constants (Ki) of lipid-metabolizing enzymes.
• Cell Biology Studies: Investigated for its role in protein S-acylation (palmitoylation) and its effects on protein localization and signaling.

Basic Information

Product Name	Oleoyl Coenzyme A
CAS No.	1716-06-9
Molecular Formula	C39H68N7O17P3S
Molecular Weight	1039.96 g/mol
Synonyms	Oleoyl-CoA; (9Z)-Octadecenoyl-CoA; cis-δ9-Octadecenoyl-Coenzyme A; Oleoyl-Coenzyme A Lithium Salt; Coenzyme A, S-oleoyl-; Oleoyl CoA; 9Z-Octadecenoyl-Coenzyme A; S-Oleoylcoenzyme A
EINECS	217-015-7

Quality Control

Our Oleoyl Coenzyme A is produced under stringent conditions to ensure the highest standards of purity and batch-to-batch consistency, suitable for sensitive research and diagnostic applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry for identity verification. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated under an inert atmosphere. Allow the vial to warm to room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder or lyophilized solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Mass spectrum matches theoretical molecular ion pattern
Purity (HPLC)	≥ 95% (Area Percent)
Water Content (KF)	≤ 5.0 %
Biological Activity	Confirmed via enzymatic assay (Contact for details)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.