Description

8-Fluoro-8-Demethylriboflavin is a strategically fluorinated derivative of the essential vitamin riboflavin (Vitamin B2). This modification introduces a fluorine atom at the 8-position, creating a valuable biochemical tool and a potential precursor for advanced pharmaceutical research. It is particularly significant for researchers and manufacturers developing novel enzyme inhibitors, fluorescent probes, and metabolic studies. This compound is essential for biochemical research, pharmaceutical development, and advanced material science applications where precise molecular modification is required.

Application

• Biochemical Research: Serves as a critical precursor or reference standard in the study of flavin-dependent enzymes and metabolic pathways.
• Pharmaceutical Intermediate: Used in the research and development of novel drug candidates, particularly enzyme inhibitors targeting specific biological processes.
• Fluorescent Probe Development: Acts as a building block for creating specialized fluorescent tags and sensors due to the modified flavin structure.
• Metabolic Studies: Employed as a tracer or analog to investigate vitamin B2 (riboflavin) metabolism and function in biological systems.
• Academic & Industrial R&D: A key material for universities and corporate R&D departments focused on medicinal chemistry and chemical biology.
• Reference Standard: Used for analytical method development, validation, and quality control in laboratories producing or analyzing flavin compounds.

Basic Information

Product Name	8-Fluoro-8-Demethylriboflavin
CAS No.	1691-79-8
Molecular Formula	C₁₇H₂₀FN₄O₆
Molecular Weight	395.36 g/mol
Synonyms	8-Fluororiboflavin; 8-Fluoro-7,8-didemethyl-10-ribitylisoalloxazine; Vitamin B2 8-fluoro analog; 8-Fluoro-7,8-didemethylriboflavin; 8-F-Riboflavin; 8-Fluoro-10-(D-ribo-2,3,4,5,6-pentahydroxypentyl)isoalloxazine
EINECS	Contact for details

Quality Control

Our 8-Fluoro-8-Demethylriboflavin is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production standards. Our quality commitment supports applications requiring high-purity biochemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider using an inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to Orange Crystalline Powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Single Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.