Description

Fructose, D-, [3H(G)] CAS NO 1684-31-7 is a high-purity, tritium-labeled derivative of D-fructose, a fundamental monosaccharide. This radiolabeled compound is essential for advanced metabolic and biochemical research, enabling precise tracking and quantification in complex biological systems. It is a critical reagent for researchers in pharmaceutical development, nutritional science, and metabolic pathway analysis who require reliable, high-specific-activity tracers.

Application

• Metabolic Pathway Tracing: Used as a radiolabeled tracer to study carbohydrate metabolism, glycolysis, and the pentose phosphate pathway in vitro and in vivo.
• Drug Metabolism Studies (ADME): Employed in Absorption, Distribution, Metabolism, and Excretion (ADME) research to investigate the metabolic fate of sugar-based pharmaceuticals or prodrugs.
• Enzyme Kinetics & Mechanism: Serves as a substrate for kinetic studies of enzymes like ketohexokinase or fructokinase to determine reaction rates and mechanisms.
• Receptor Binding Assays: Utilized in research on sugar transporters (e.g., GLUT5) and receptors to study binding affinity and cellular uptake mechanisms.
• Nutritional Research: Applied in studies investigating fructose absorption, liver metabolism, and its role in conditions like metabolic syndrome.
• Biochemical Synthesis Monitoring: Acts as a labeled precursor for tracking the incorporation of fructose into more complex carbohydrates, glycoconjugates, or natural products.

Basic Information

Item	Detail
Product Name	Fructose, D-, [3H(G)]
CAS No.	1684-31-7
Molecular Formula	C6H12O6 (³H labeled)
Molecular Weight	~180.16 g/mol (³H labeled)
Synonyms	D-(-)-Fructose, tritium-labeled; [G-³H]-D-Fructose; Levulose, tritiated; Fruit sugar, labeled; (3R,4S,5R)-1,3,4,5,6-Pentahydroxyhexan-2-one-³H; β-D-Fructopyranose-³H; Radioactive D-fructose
EINECS	Contact for details

Quality Control

Every batch of our tritium-labeled D-fructose is manufactured and analyzed under strict quality systems. We guarantee high radiochemical purity and specific activity as specified. Comprehensive quality control includes verification by HPLC with radiometric detection. A detailed Certificate of Analysis (COA), documenting specific activity, radiochemical purity, chemical purity, and solvent composition, is provided with each shipment to ensure compliance with your research protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep the primary container in a sealed secondary container with desiccant. Handle and dispose of in accordance with all applicable radiation safety regulations and guidelines.

Specification

Item	Specification
Appearance	Clear, colorless solution
Specific Activity	Customizable (e.g., 10-100 Ci/mmol)
Radiochemical Purity (HPLC)	≥ 95%
Chemical Purity (HPLC)	≥ 98%
Concentration	1 mCi/mL (as specified)
Solvent	Ethanol:Water mixture (specified ratio)
Radionuclidic Identity	³H (Tritium)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.