Description

(2α,5β,6α,18β)-Ibogamine is a complex indole alkaloid and a key structural derivative of the naturally occurring iboga alkaloids. This compound is of significant interest in advanced pharmaceutical research and development due to its unique polycyclic framework. It serves as a critical intermediate and reference standard for researchers in neuropharmacology, medicinal chemistry, and analytical laboratories globally.

Application

• Pharmaceutical Research Intermediate: Serves as a crucial building block in the synthesis and development of novel therapeutic agents targeting neurological pathways.
• Reference Standard for Analytical Testing: Used in HPLC, LC-MS, and NMR for method development, validation, and quality control of related alkaloid substances.
• Medicinal Chemistry Studies: Employed in structure-activity relationship (SAR) studies to understand the pharmacophore of iboga alkaloids and design new analogs.
• Neuroscience Research: Utilized as a biochemical tool in preclinical studies to investigate interactions with specific receptor systems in the central nervous system.
• Academic and Institutional Research: A key compound for universities and research institutes studying natural product chemistry and alkaloid biosynthesis.

Basic Information

Product Name	(2α,5β,6α,18β)-Ibogamine
CAS No.	1673-99-0
Molecular Formula	C19H24N2
Molecular Weight	280.41 g/mol
Synonyms	Ibogamine; (2α,5β,6α,18β)-Ibogamine; 19-Epiibogamine; 19-epi-Ibogamine; 2α,5β,6α,18β-Ibogamine; NSC 165563; 3-Ethyl-2,3,4,5,6,7-hexahydro-1H-2,6-methano-1-benzazocin-11-ol
EINECS	Contact for details

Quality Control

Our (2α,5β,6α,18β)-Ibogamine is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for research applications. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.