Description

R,S-Tetrahydropapaverine is a synthetic isoquinoline alkaloid derivative of significant interest in pharmaceutical research and development. This compound serves as a key intermediate and a versatile building block for the synthesis of more complex bioactive molecules. It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in the development of central nervous system (CNS) agents and other therapeutic candidates.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential vasodilators, antispasmodics, and other pharmacologically active isoquinoline derivatives.
• Neurological Research: Used as a reference standard and a starting material in studies targeting neurotransmitter pathways and receptor interactions within the CNS.
• Chemical Synthesis: Serves as a versatile chiral building block for organic chemists developing novel heterocyclic compounds with potential biological activity.
• Analytical Standard: Employed as a high-purity standard in analytical laboratories for method development, validation, and quality control (HPLC, GC, LC-MS).
• Biochemical Tool Compound: Utilized in in-vitro assays to study enzyme inhibition and other biochemical mechanisms related to its structural class.

Basic Information

Product Name	R,S-Tetrahydropapaverine
CAS No.	1654-28-0
Molecular Formula	C₂₀H₂₅NO₄
Molecular Weight	343.42 g/mol
Synonyms	1-[(3,4-Dimethoxyphenyl)methyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline; (±)-Tetrahydropapaverine; DL-Tetrahydropapaverine; NSC 169865; THP; Laudanosine derivative
EINECS	Contact for details

Quality Control

Our R,S-Tetrahydropapaverine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification (IR, NMR), purity determination by HPLC, and control of specific impurities to ensure it meets the stringent requirements for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.