Description

(3S,8S,9S,10R,13R,14S,17R)-10,13-Dimethyl-17-[(2R)-6-Methylheptan-2-Yl]-3-Sulfooxy-2,3,4,7,8,9,11,12,14,15,16,17-Dodecahydro-1H-Cyclopenta[A]Phenanthrene is a high-purity, sulfated steroid derivative of significant interest in advanced biochemical research and pharmaceutical development. This compound serves as a critical reference standard and synthetic intermediate for the study of steroid metabolism, receptor interactions, and the development of novel therapeutic agents. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require precisely characterized molecules for their development pipelines.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis (HPLC, LC-MS) of steroid-based drugs and metabolites in quality control laboratories.
• Biochemical Research: A key intermediate in studying steroid sulfation pathways, enzyme kinetics (sulfotransferases), and hormone regulation mechanisms.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a sophisticated building block in the multi-step synthesis of complex steroid-derived therapeutics.
• Metabolite Identification: Employed in drug metabolism and pharmacokinetics (DMPK) studies to identify and characterize sulfated metabolites of lead compounds.
• Academic Research: Utilized in universities and research institutes for fundamental studies in organic chemistry, medicinal chemistry, and endocrinology.
• Diagnostic Development: Potential use in the development of calibration standards for clinical diagnostic assays measuring steroid hormone levels.

Basic Information

Item	Detail
Product Name	(3S,8S,9S,10R,13R,14S,17R)-10,13-Dimethyl-17-[(2R)-6-Methylheptan-2-Yl]-3-Sulfooxy-2,3,4,7,8,9,11,12,14,15,16,17-Dodecahydro-1H-Cyclopenta[A]Phenanthrene
CAS No.	1491-95-8
Molecular Formula	C27H46O4S
Molecular Weight	466.72 g/mol
Synonyms	Cholesteryl Sulfate; Cholesterol 3-Sulfate; 3β-Hydroxycholest-5-en-3-yl Sulfate; 5-Cholesten-3β-ol Sulfate; NSC 4911; Cholest-5-en-3β-ol Sulfate; (3β)-Cholest-5-en-3-yl Sulfate; 3β-Sulfoxy-5-cholestene
EINECS	Contact for details

Quality Control

Our production of this high-value biochemical adheres to strict quality management systems. Each batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity and purity. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing assay, impurity profile, and physical characteristics. We support compliance with cGMP guidelines for materials intended for pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.