Description

Hydroquinidine is a cinchona alkaloid derivative, closely related to quinine and quinidine, known for its distinct stereochemistry and biological activity. This compound serves as a valuable chiral building block and resolving agent in asymmetric synthesis, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. It is essential for research and development laboratories, pharmaceutical manufacturers, and chemical synthesis specialists requiring high-purity chiral intermediates or catalysts.

Application

• Asymmetric Synthesis Catalyst: Employed as a chiral ligand or phase-transfer catalyst in enantioselective reactions.
• Pharmaceutical Intermediate: Used in the research and synthesis of active pharmaceutical ingredients (APIs), particularly those targeting cardiac and antimalarial applications.
• Chiral Resolution Agent: Utilized for the separation of racemic mixtures of carboxylic acids and other compounds via diastereomeric salt formation.
• Analytical Standard: Serves as a high-purity reference standard in chromatographic analysis and quality control for related alkaloids.
• Biochemical Research: Investigated for its effects on ion channels and as a tool compound in pharmacological studies.
• Fine Chemical Synthesis: Acts as a precursor or intermediate in the synthesis of more complex, specialty organic molecules.

Basic Information

Product Name	Hydroquinidine
CAS No.	1435-55-8
Molecular Formula	C20H26N2O2
Molecular Weight	326.44 g/mol
Synonyms	10,11-Dihydroquinidine; (8S,9R)-10,11-Dihydro-6'-methoxycinchonan-9-ol; Dihydroquinidine; Hydrochinidine; Hydroconquinine; Quinotoxine; NSC 221154; β-Quinidine
EINECS	215-857-9

Quality Control

Our Hydroquinidine is produced and tested under a strict quality management system. Each batch is analyzed to ensure high chemical purity and identity, with specifications typically meeting or exceeding standard reagent-grade requirements. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Specific Rotation	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.