Description

Ranaconitine is a diterpenoid alkaloid derived from specific Aconitum species, known for its complex molecular structure and significant biological activity. This high-purity reference standard is critical for pharmaceutical research and development, particularly in the study of natural product pharmacology and toxicology. It is primarily utilized by research institutions, pharmaceutical companies, and analytical laboratories engaged in drug discovery, phytochemical analysis, and the development of analytical methods.

Application

• Pharmaceutical Reference Standard: Serves as a certified primary standard for the identification, assay, and purity testing of related alkaloids in raw materials and finished products.
• Biochemical Research: Used as a key reagent in studies investigating the mechanism of action, metabolism, and structure-activity relationships (SAR) of diterpenoid alkaloids.
• Analytical Method Development: Employed for the calibration and validation of analytical instruments such as HPLC, LC-MS, and NMR in quality control laboratories.
• Natural Product Isolation & Purification: Acts as a benchmark compound for the isolation, purification, and characterization of alkaloids from plant extracts.
• Toxicology Studies: Utilized in research focused on the toxicological profile and safety assessment of Aconitum-derived compounds.

Basic Information

Product Name	Ranaconitine
CAS No.	1360-76-5
Molecular Formula	C35H49NO10
Molecular Weight	643.77 g/mol
Synonyms	Ranaconitin; Ranaconitine; (1α,6α,14α,16β)-20-Ethyl-1,6,16-trimethoxy-4-(methoxymethyl)aconitane-7,8,14-triol 8-acetate 14-benzoate; Aconitane-7,8,14-triol, 20-ethyl-1,6,16-trimethoxy-4-(methoxymethyl)-, 8-acetate 14-benzoate, (1α,6α,14α,16β)-
EINECS	Contact for details

Quality Control

Our Ranaconitine is produced and tested under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting batch-specific results.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.