Description

(16R)-18,19-Didehydro-17-Hydroxycorynan-16-Carboxylic Acid Methyl Ester is a high-purity, complex indole alkaloid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a critical intermediate or reference standard for the development of novel therapeutic agents, particularly those targeting neurological and cardiovascular systems. It is essential for research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the synthesis of complex natural products and bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex indole alkaloids and potential active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard or probe in pharmacological studies to investigate biological pathways and receptor interactions.
• Organic Synthesis: Serves as a sophisticated starting material or intermediate for academic and industrial research in total synthesis and methodology development.
• Analytical Standard: Provides a high-purity benchmark for quality control and analytical method development (e.g., HPLC, LC-MS) in related chemical processes.

Basic Information

Item	Detail
Product Name	(16R)-18,19-Didehydro-17-Hydroxycorynan-16-Carboxylic Acid Methyl Ester
CAS No.	1245-00-7
Molecular Formula	C21H24N2O3
Molecular Weight	352.43 g/mol
Synonyms	Methyl (16R)-18,19-didehydro-17-hydroxycorynan-16-carboxylate; 16R-18,19-Didehydro-17-hydroxycorynan-16-carboxylic acid methyl ester; Yohimbine derivative; 3-Epi-α-yohimbine methyl ester; Corynan-16-carboxylic acid, 18,19-didehydro-17-hydroxy-, methyl ester, (16R)-; Methyl 18,19-didehydro-17-hydroxycorynan-16R-carboxylate
EINECS	Contact for details

Quality Control

Our (16R)-18,19-Didehydro-17-Hydroxycorynan-16-Carboxylic Acid Methyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Loss on Drying	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.