Description

H-Gly-Pna is a specialized peptide derivative and a key chemical intermediate widely used in organic synthesis and pharmaceutical research. Its primary value lies in its role as a building block for constructing more complex peptide structures and as a chromogenic substrate in enzymatic assays. This compound is essential for research and development laboratories in the pharmaceutical, biotechnology, and life sciences sectors, where precise molecular tools are required for drug discovery and biochemical analysis.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel peptide-based drug candidates and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a chromogenic substrate for studying enzyme kinetics, particularly for proteases like trypsin and chymotrypsin, enabling colorimetric detection of enzymatic activity.
• Proteomics & Diagnostics: Employed in the development of diagnostic assays and research kits for protein analysis and biomarker detection.
• Organic Synthesis: Acts as a protected glycine derivative for the solid-phase and solution-phase synthesis of custom peptides and peptidomimetics.
• Academic Research: A valuable tool in university and institutional labs for teaching and investigating peptide chemistry and enzymatic mechanisms.

Basic Information

Product Name	H-Gly-Pna
CAS No.	1205-88-5
Molecular Formula	C9H11N3O3
Molecular Weight	209.20 g/mol
Synonyms	Glycine 4-nitroanilide; Gly-pNA; H-Glycine-p-nitroanilide; N-(4-Nitrophenyl)glycinamide; Glycine p-nitroanilide; 4-Nitroanilide of glycine; Glycine-4-nitroaniline; Substrate for trypsin
EINECS	214-889-8

Quality Control

Our H-Gly-Pna is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity assessment and identity confirmation via spectroscopic methods. A detailed Certificate of Analysis (COA) documenting purity, physical characteristics, and test results is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.