Description

5-Formyluracil is a high-purity pyrimidine derivative and a key modified nucleobase with significant research and synthetic utility. Its primary value lies in its role as a versatile building block for the synthesis of oligonucleotides and as a critical intermediate in the study of DNA damage and repair mechanisms. This compound is essential for researchers and manufacturers in the fields of pharmaceutical development, diagnostic probe synthesis, and academic biochemistry.

Application

• Oligonucleotide Synthesis: A crucial precursor for incorporating modified bases into synthetic DNA and RNA strands for therapeutic and diagnostic applications.
• Biochemical Research: Used as a substrate or standard in studies of oxidative DNA damage, repair enzyme activity, and mutagenesis.
• Pharmaceutical Intermediates: Serves as a key building block in the development of novel nucleoside-based antiviral and anticancer agents.
• Diagnostic Reagents: Employed in the manufacture of probes and assays for detecting specific genetic markers or DNA lesions.
• Academic & Industrial R&D: Fundamental material for exploring novel nucleic acid chemistry and developing advanced biomaterials.

Basic Information

Product Name	5-Formyluracil
CAS No.	1195-08-0
Molecular Formula	C5H4N2O3
Molecular Weight	140.10 g/mol
Synonyms	5-Carboxaldehyde uracil; Isobarbituric acid; 5-Formyl-2,4(1H,3H)-pyrimidinedione; 5-FUra; 5-FU; 5-Formyl-1H-pyrimidine-2,4-dione; 5-Oxomethyluracil
EINECS	214-806-7

Quality Control

Our 5-Formyluracil is produced under a strict quality management system to ensure batch-to-batch consistency and high purity for research and synthesis. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and hygroscopic (moisture-sensitive); ensure containers are sealed after each use to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.