Description

γ-Hydroxyvitamin K is a specific, biologically relevant derivative of Vitamin K, distinguished by the presence of a hydroxyl group on the gamma position of its side chain. This compound is critical for research and development in biochemistry and pharmacology, particularly in studies related to blood coagulation, bone metabolism, and cellular signaling pathways. It serves as a key intermediate and reference standard for manufacturers and research institutions focused on vitamin metabolism, anticoagulant drug development, and nutritional science.

Application

• Pharmaceutical Reference Standard: Used as a high-purity analytical standard for quality control and method validation in the production of Vitamin K-related pharmaceuticals and supplements.
• Biochemical Research: Essential for in-vitro and in-vivo studies investigating the role of Vitamin K derivatives in the γ-carboxylation of glutamate residues in proteins (e.g., clotting factors, osteocalcin).
• Nutraceutical Development: Acts as a precursor or an active ingredient in advanced formulations targeting bone health and cardiovascular support.
• Metabolic Pathway Analysis: Employed in laboratories to study the metabolic conversion and biological activity of different Vitamin K forms.
• Academic & Clinical Research: Supports fundamental research in hematology, endocrinology, and molecular biology at universities and clinical institutes.

Basic Information

Product Name	γ-Hydroxyvitamin K
CAS No.	1181-23-3
Molecular Formula	C31H46O3
Molecular Weight	466.70 g/mol
Synonyms	Vitamin K1 Hydroxy Derivative; γ-Hydroxyphylloquinone; 2-Methyl-3-(3-hydroxyphytyl)-1,4-naphthoquinone; 3-Phytylmenadiol-1,4-naphthoquinone; 2-Methyl-3-(γ-hydroxyphytyl)-1,4-naphthoquinone; Hydroxy Vitamin K1; Phylloquinone Hydroxy Derivative
EINECS	Contact for details

Quality Control

Our γ-Hydroxyvitamin K is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to minimize oxidation and degradation. The container should be kept in a cool, dry, and well-ventilated area away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.