Description

Jatrorrhizine Hydrochloride is a bioactive isoquinoline alkaloid salt derived from various medicinal plants, including *Tinospora cordifolia* and *Coptis chinensis*. This high-purity compound is valued for its significant pharmacological properties, making it a critical reference standard and active ingredient in advanced research and development. It is primarily sought by the pharmaceutical, nutraceutical, and life science research industries for applications in metabolic, neurological, and antimicrobial studies.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for quality control and analytical method development in drug manufacturing.
• Biomedical Research: Serves as a key tool in preclinical studies investigating its effects on diabetes, hyperlipidemia, and insulin resistance.
• Neurological Research: Employed in studies exploring potential neuroprotective and anti-depressant mechanisms.
• Antimicrobial Agent Development: Investigated for its activity against various bacterial, fungal, and protozoal pathogens.
• Natural Product & Nutraceutical Formulation: Incorporated into standardized herbal extracts and dietary supplements for metabolic health support.
• Biochemical Assays: Used as a substrate or inhibitor in enzymatic and receptor-binding assays to study biological pathways.

Basic Information

Product Name	Jatrorrhizine Hydrochloride
CAS No.	1168-00-9
Molecular Formula	C20H20NO4·HCl
Molecular Weight	383.84 g/mol
Synonyms	Jatrorrhizine HCl; Jatrorhizine Hydrochloride; (13-Methyl-2,3,9,10-tetramethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinolin-5-yl)methanol hydrochloride; NSC 329689; Yatrorizine Hydrochloride; Coptisine chloride (related); Neprotin (related)
EINECS	Contact for details

Quality Control

Our Jatrorrhizine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and MS, and residual solvent analysis to ensure it meets high-grade standards suitable for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	Yellow to orange-yellow powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥98.0%
Loss on Drying	≤2.0%
Residue on Ignition	≤0.5%
Heavy Metals (as Pb)	≤20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.