Description

(3A,5B,7A,12A)- 3,7,12,24-Tetrahydroxy-Cholestan-26-Oic Acid is a high-purity, multi-hydroxylated bile acid derivative, a key intermediate in the synthesis of complex steroidal compounds. Its precise stereochemistry and functional groups make it a valuable building block for pharmaceutical research and development. This compound is essential for researchers and manufacturers in the life sciences sector focusing on metabolic pathways, drug discovery, and the production of specialized biochemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel therapeutic agents targeting liver and metabolic diseases.
• Biochemical Research: Used as a reference standard and reagent in studies of bile acid metabolism, cholesterol homeostasis, and related enzymatic pathways.
• Steroid Chemistry: Serves as a versatile chiral starting material for the preparation of complex steroidal structures with specific biological activity.
• Metabolite Standard: Employed in analytical laboratories for the calibration and validation of LC-MS/MS and HPLC methods in clinical and diagnostic testing.
• Enzyme Substrate/Inhibitor Studies: Utilized in vitro to investigate the function and kinetics of enzymes involved in steroid and bile acid biosynthesis.

Basic Information

Product Name	(3A,5B,7A,12A)- 3,7,12,24-Tetrahydroxy-Cholestan-26-Oic Acid
CAS No.	1061-64-9
Molecular Formula	C27H46O6
Molecular Weight	466.66 g/mol
Synonyms	3α,7α,12α,24-Tetrahydroxy-5β-cholestan-26-oic Acid; 3α,7α,12α,24-Tetrahydroxy-5β-cholan-26-oic Acid; 24-Hydroxy-3,7,12-trihydroxy-5β-cholestan-26-oate; Tetrahydroxycholestanoic Acid; 5β-Cholestane-3α,7α,12α,24-tetrol-26-oic Acid; (3α,5β,7α,12α)-3,7,12,24-Tetrahydroxycholestan-26-oic Acid
EINECS	Contact for details

Quality Control

Our (3A,5B,7A,12A)- 3,7,12,24-Tetrahydroxy-Cholestan-26-Oic Acid is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. Custom purity grades and analytical packages are available to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). For long-term stability, storage at -20°C under an inert atmosphere is recommended. The material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.