Description

Protoveratrine A is a potent, naturally occurring steroidal alkaloid derived from plants of the *Veratrum* genus. This high-purity compound is critical for pharmaceutical research and development, particularly in the study of cardiovascular and neurological mechanisms. It serves as a key reference standard and active pharmaceutical ingredient (API) intermediate for researchers and manufacturers in the life sciences sector. Global demand is driven by its specific biological activity and application in advanced therapeutic studies.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for quality control and analytical method development in pharmacopeial testing.
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a critical building block in the synthesis of specialized pharmaceutical compounds.
• Biochemical Research: Employed in pharmacological studies to investigate its effects on sodium channels and as a tool compound in neurobiological and cardiovascular research.
• Analytical Chemistry: Utilized as a high-purity standard for calibration in chromatographic (HPLC, LC-MS) and spectroscopic analyses.
• Toxicology Studies: Applied in research concerning plant alkaloid toxicity and the development of corresponding antidotes or treatments.

Basic Information

Product Name	Protoveratrine A
CAS No.	143-57-7
Molecular Formula	C41H63NO13
Molecular Weight	793.94 g/mol
Synonyms	Protoveratrine A; Veratrine, proto-; 3,4,12,14,16,17,20-Heptahydroxy-4,9-epoxycevan-6-one 3,4-diacetate 12,14-dipropionate; NSC 209816; Protoveratrin A; (3β,4α,6β,15α,16β)-4,9-Epoxycevane-3,4,6,14,15,16,17,20-octol 3,6-diacetate 15,16-dipropanoate; Veratrum alkaloid
EINECS	205-615-5

Quality Control

Our Protoveratrine A is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and MS for identification, and residual solvent analysis to ensure it meets stringent specifications for research and pharmaceutical use. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with the agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.