Description

Berbine CAS NO 131-10-2 is a naturally occurring isoquinoline alkaloid of significant interest in pharmaceutical and biochemical research. This compound serves as a crucial intermediate and reference standard for the development of novel therapeutic agents. It is primarily utilized by research institutions, pharmaceutical developers, and manufacturers of high-purity fine chemicals. Its defined structure and properties make it a valuable building block for synthetic chemistry and pharmacological studies.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of more complex alkaloids and potential drug candidates targeting various biological pathways.
• Biochemical Research: Used as a reference standard and tool compound in pharmacological studies to investigate biological activity and mechanism of action.
• Analytical Standard: Employed in quality control laboratories for method development, calibration, and identification via techniques like HPLC and mass spectrometry.
• Natural Product Chemistry: Integral to the study, isolation, and characterization of plant-derived alkaloids and their derivatives.
• Academic Research: Utilized in university and institutional labs for educational purposes and fundamental chemical research.

Basic Information

Product Name	Berbine
CAS No.	131-10-2
Molecular Formula	C₂₀H₂₁NO₄
Molecular Weight	339.39 g/mol
Synonyms	9,10-Dimethoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinoline; 5,6-Dihydro-9,10-dimethoxybenzo[g]-1,3-benzodioxolo[5,6-a]quinolizine; Berbin; Berbinum; NSC 11905; Tetrahydroberberine; Canadine (Note: Canadine is a specific stereoisomer of berbine)
EINECS	205-025-6

Quality Control

Our Berbine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing specific results for parameters such as HPLC purity, residual solvents, and heavy metals are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.