Description

Methyl (3Beta,19Alpha,20Alpha)-16,17-Didehydro-10,11-Dimethoxy-19-Methyloxayohimban-16-Carboxylate CAS NO 131-02-2 is a complex, high-purity indole alkaloid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a critical intermediate for developing novel therapeutic agents, particularly those targeting neurological and cardiovascular pathways. It is primarily utilized by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers engaged in the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex alkaloid-based active pharmaceutical ingredients (APIs).
• Neurological Research: Used as a precursor in the development of compounds for studying neurotransmitter receptors and related neurological disorders.
• Cardiovascular Drug Discovery: Serves as a starting material for synthesizing potential agents that modulate blood pressure and vascular function.
• Organic Synthesis Reference Standard: Employed as a high-purity reference compound for method development and validation in analytical chemistry.
• Medicinal Chemistry: Integral for structure-activity relationship (SAR) studies to optimize the biological profile of new chemical entities.
• Biochemical Research: Used in the study of enzyme inhibition and other biochemical mechanisms due to its specific structural features.

Basic Information

Product Name	Methyl (3Beta,19Alpha,20Alpha)-16,17-Didehydro-10,11-Dimethoxy-19-Methyloxayohimban-16-Carboxylate
CAS No.	131-02-2
Molecular Formula	C23H26N2O5
Molecular Weight	410.47 g/mol
Synonyms	10,11-Dimethoxy-19-methyl-16,17-didehydrooxayohimban-16-carboxylic acid methyl ester; Methyl 10,11-dimethoxy-19-methyl-16,17-didehydrooxayohimban-16-carboxylate; Yohimbine analog; 19-Methyl-10,11-dimethoxy-16,17-didehydrooxayohimban-16-carboxylic acid methyl ester; (3β,19α,20α)-16,17-Didehydro-10,11-dimethoxy-19-methyloxayohimban-16-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl (3Beta,19Alpha,20Alpha)-16,17-Didehydro-10,11-Dimethoxy-19-Methyloxayohimban-16-Carboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.