Description

(8Alpha,9R)-10,11-Dihydro-6'-[(6-Methylheptyl)Oxy]Cinchonan-9-Ol is a high-purity cinchona alkaloid derivative, a key chiral building block and ligand in asymmetric synthesis. Its primary commercial value lies in its role as a precursor for the synthesis of advanced pharmaceutical intermediates and as a versatile catalyst in stereoselective reactions. This compound is essential for research and production in the fine chemical, pharmaceutical, and agrochemical industries, where precise control over molecular chirality is critical.

Application

• Asymmetric Synthesis Catalyst: Used as a chiral ligand or catalyst in enantioselective transformations such as Sharpless dihydroxylation and other oxidation reactions.
• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of active pharmaceutical ingredients (APIs) requiring specific stereochemistry.
• Chiral Resolution Agent: Employed in the separation of racemic mixtures to isolate enantiomerically pure compounds.
• Fine Chemical Synthesis: Utilized in the production of specialty chemicals, flavors, and fragrances where stereochemical purity is paramount.
• Research & Development: A valuable tool in academic and industrial R&D for developing new synthetic methodologies and chiral compounds.
• Agrochemical Production: Used in the synthesis of chiral pesticides and herbicides to enhance efficacy and reduce environmental impact.

Basic Information

Product Name	(8Alpha,9R)-10,11-Dihydro-6'-[(6-Methylheptyl)Oxy]Cinchonan-9-Ol
CAS No.	130-87-0
Molecular Formula	C₂₁H₃₂N₂O₂
Molecular Weight	344.49 g/mol
Synonyms	10,11-Dihydro-6'-[(6-methylheptyl)oxy]cinchonan-9-ol; Dihydroquinidine 6'-O-(6-methylheptyl) ether; (8α,9R)-10,11-Dihydro-6'-[(6-methylheptyl)oxy]cinchonan-9-ol; Dihydroquinidine alkyl ether derivative; Cinchona alkaloid derivative; Chiral dihydroquinidine ether; Asymmetric catalyst ligand; Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our (8Alpha,9R)-10,11-Dihydro-6'-[(6-Methylheptyl)Oxy]Cinchonan-9-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat and incompatible materials. Due to its light-sensitive nature, containers should be opaque or stored in darkness.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.