Description

Mu-Conotoxin CAS NO 936616-33-0 is a highly specific, synthetic peptide toxin derived from cone snail venom. This compound is a valuable research tool for selectively blocking voltage-gated sodium channels, particularly the Nav1.4 subtype. It is essential for researchers in neuroscience and pharmacology studying neuromuscular function, pain pathways, and ion channel biophysics. Our product is supplied to the highest purity standards to ensure reliable and reproducible experimental results.

Application

• Neuroscience Research: As a selective pharmacological agent for studying the function and distribution of voltage-gated sodium channels (Nav1.4) in neuronal and muscular tissues.
• Ion Channel Pharmacology: Used in electrophysiology assays (e.g., patch-clamp) to characterize sodium channel kinetics, inactivation properties, and subtype specificity.
• Drug Discovery & Development: Serves as a reference standard and tool compound in high-throughput screening (HTS) campaigns for identifying novel analgesics or sodium channel modulators.
• Toxicology Studies: Employed to investigate the mechanisms of natural venoms and to develop potential therapeutic applications from toxin analogs.
• Biochemical Assays: Used in binding studies and competitive displacement assays to measure receptor-ligand interactions.
• Academic & Institutional Research: A critical reagent for universities and research institutes focused on cellular signaling, neurobiology, and molecular physiology.

Basic Information

Product Name	Mu-Conotoxin
CAS No.	936616-33-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	μ-Conotoxin; Mu-Conotoxin PIIIA; Conotoxin μ-PIIIA; μ-PIIIA; Mu-Conotoxin PnIA; Sodium channel blocker peptide; Cone snail toxin μ-PIIIA; μ-Conotoxin GIIIA (related analog); SNX-482 (related analog, different target)
EINECS	Contact for details

Quality Control

Every batch of Mu-Conotoxin is produced and analyzed under strict quality management protocols to ensure the highest purity and biological activity. Our products undergo rigorous quality testing, including multiple orthogonal analytical methods, to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and bioactivity is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. Aliquot into single-use vials to minimize freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Biological Activity (Cell-based assay)	IC50 provided on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.