Description

n-[Tris(Hydroxymethyl)Methyl]-3-Aminopropanesulfonic Acid Sodium Salt is a high-purity, zwitterionic biological buffer salt essential for maintaining stable pH in sensitive biochemical systems. Its primary value lies in its excellent buffering capacity in the physiological pH range, combined with low UV absorbance and minimal interference with biological processes. This makes it a critical reagent for molecular biology research, pharmaceutical development, and diagnostic manufacturing, where precise and non-interfering pH control is paramount.

Application

• Biochemical & Molecular Biology Buffers: A key component in electrophoresis (e.g., TAPS buffer), cell culture media, and enzyme reaction mixtures.
• Pharmaceutical Formulation: Used as an excipient or buffering agent in parenteral solutions, diagnostic kits, and vaccine stabilizers.
• Protein Purification & Analysis: Employed in chromatography (HPLC, FPLC) and protein crystallization due to its high purity and low metal ion content.
• Diagnostic Reagents: Integral to the formulation of clinical chemistry reagents and immunoassay buffers for consistent performance.
• Tissue Culture & Cell-Based Assays: Provides a stable, non-toxic pH environment for mammalian and bacterial cell growth.
• Cosmetic & Personal Care: Acts as a pH stabilizer and conditioning agent in high-end skincare and haircare formulations.

Basic Information

Product Name	n-[Tris(Hydroxymethyl)Methyl]-3-Aminopropanesulfonic Acid Sodium Salt
CAS No.	91000-53-2
Molecular Formula	C7H16NNaO6S
Molecular Weight	265.26 g/mol
Synonyms	TAPS Sodium Salt; Sodium TAPS; 3-[(1,3-Dihydroxy-2-(hydroxymethyl)propan-2-yl)amino]propane-1-sulfonic acid sodium salt; TAPS Na; N-[Tris(hydroxymethyl)methyl]-3-aminopropanesulfonic acid sodium salt; TAPS buffer salt; (2-Hydroxy-1,1-bis(hydroxymethyl)ethyl)amino-1-propanesulfonic acid sodium salt; Good's Buffer TAPS sodium salt
EINECS	Contact for details

Quality Control

Our n-[Tris(Hydroxymethyl)Methyl]-3-Aminopropanesulfonic Acid Sodium Salt is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity, ICP-MS for heavy metals, and comprehensive identity confirmation, to ensure it meets the stringent requirements for life science and pharmaceutical applications. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed in a dry environment to prevent absorption of moisture and caking.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
pH (1% Solution)	7.0 - 8.0
Loss on Drying	≤ 1.0%
Heavy Metals (as Pb)	≤ 10 ppm
UV Absorbance (260 nm)	≤ 0.05
Endotoxin (where applicable)	< 0.25 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.