Description

N,N'-Disuccinimidyl Carbonate is a high-purity, bifunctional chemical reagent widely used as a versatile coupling agent. Its primary value lies in its ability to efficiently activate carboxylic acids, forming active NHS esters for subsequent amide bond formation under mild conditions. This compound is essential for researchers and manufacturers in pharmaceutical development, peptide synthesis, bioconjugation, and proteomics, where reliable and efficient cross-linking is critical.

Application

• Peptide Synthesis: A key reagent for activating amino acids and facilitating peptide chain elongation.
• Bioconjugation & Protein Labeling: Used to cross-link proteins, antibodies, or enzymes with other biomolecules, dyes, or solid supports.
• Polymer & Material Science: Employed in the surface modification of polymers and the synthesis of functionalized biomaterials.
• Proteomics Research: Facilitates the preparation of affinity matrices and the immobilization of ligands for study.
• Diagnostic Reagent Manufacturing: Integral in creating stable conjugates for immunoassays and diagnostic kits.
• Small Molecule Drug Development: Enables the synthesis of amide-linked prodrugs and active pharmaceutical ingredients (APIs).

Basic Information

Product Name	N,N'-Disuccinimidyl Carbonate
CAS No.	74124-79-1
Molecular Formula	C9H8N2O8
Molecular Weight	272.17 g/mol
Synonyms	DSC; N,N'-Disuccinimidyl Carbonate; Disuccinimidyl Carbonate; Succinimidyl Carbonate; Carbonyl Di(Succinimidyl) Carbonate; NSC 261047; Bis(N-succinimidyl) Carbonate; 2,5-Dioxopyrrolidin-1-yl 2,5-dioxopyrrolidin-1-yl carbonate
EINECS	Contact for details

Quality Control

Our N,N'-Disuccinimidyl Carbonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	190 - 195 °C
Water Content (KF)	≤ 0.5%
Solubility	Soluble in DMF, DMSO, acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.