Description

n-(Tris(Hydroxymethyl)Methyl)-2-Aminoethanesulfonic Acid Sodium Salt is a high-purity biochemical buffer salt essential for maintaining stable pH in sensitive biological and chemical systems. Its primary value lies in its excellent buffering capacity in the physiological pH range, combined with high water solubility and minimal interference with biochemical processes. This makes it a critical reagent for pharmaceutical formulation, diagnostic kit manufacturing, and advanced life science research, where precise and consistent pH control is non-negotiable.

Application

• Pharmaceutical Buffer Agent: Used in the formulation of injectables, ophthalmic solutions, and cell culture media where precise physiological pH is required.
• Diagnostic Reagent Component: Serves as a key buffering component in enzyme-based diagnostic assays, test strips, and clinical analyzer solutions.
• Biochemical Research: Essential for creating stable buffer systems in protein purification, electrophoresis, PCR, and other molecular biology techniques.
• Cell Culture & Tissue Engineering: Provides a non-toxic, consistent pH environment for mammalian cell culture and bioprocessing applications.
• Cosmetic & Personal Care Formulations: Employed as a pH stabilizer in high-end skincare and haircare products requiring gentle, skin-compatible buffers.

Basic Information

Item	Detail
Product Name	n-(Tris(Hydroxymethyl)Methyl)-2-Aminoethanesulfonic Acid Sodium Salt
CAS No.	70331-82-7
Molecular Formula	C6H14NNaO7S
Molecular Weight	267.24 g/mol
Synonyms	TES Sodium Salt; Sodium TES; 2-[[1,3-Dihydroxy-2-(hydroxymethyl)propan-2-yl]amino]ethanesulfonic Acid Sodium Salt; N-[Tris(hydroxymethyl)methyl]-2-aminoethanesulfonic Acid Sodium Salt; (2-Hydroxy-1,1-bis(hydroxymethyl)ethyl)amino]methanesulfonic Acid Sodium Salt; TAPS Sodium Salt (common misnomer, but often searched); Biological Buffer Sodium Salt
EINECS	Contact for details

Quality Control

Every batch of our n-(Tris(Hydroxymethyl)Methyl)-2-Aminoethanesulfonic Acid Sodium Salt is manufactured under a strict quality management system. We provide comprehensive analytical testing to ensure the product meets the high-purity standards required for pharmaceutical and diagnostic applications. A detailed Certificate of Analysis (COA), including assay, impurity profile, and identity confirmation, is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed immediately after use to prevent absorption of atmospheric moisture, which can affect purity and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
pH (1% Solution)	6.5 - 7.5
Loss on Drying	≤ 2.0%
Heavy Metals (as Pb)	≤ 10 ppm
Residue on Ignition (Sulfated Ash)	Conforms
Endotoxin (where applicable)	< 0.25 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.