Description

Taps CAS NO 29915-38-6 is a specialized chemical compound widely utilized as a high-purity reagent in advanced biochemical and pharmaceutical research. Its primary value lies in its role as a selective and potent inhibitor of the enzyme tankyrase, a key target in oncology and regenerative medicine studies. This product is essential for researchers and developers in the fields of cancer biology, stem cell research, and molecular diagnostics who require reliable, high-quality inhibitors for pathway analysis and drug discovery.

Application

• Oncology Research: Used as a tankyrase inhibitor to study the Wnt/β-catenin signaling pathway, a critical target in colorectal, breast, and other cancers.
• Stem Cell Biology: Employed to modulate telomere length and telomerase activity in pluripotent stem cell cultures and regenerative medicine applications.
• Molecular Diagnostics: Serves as a key reagent in developing assays for telomere maintenance mechanisms and associated genetic disorders.
• Drug Discovery & Development: A vital tool compound for high-throughput screening (HTS) and lead optimization in pharmaceutical R&D targeting tankyrase.
• Biochemical Assays: Used in enzymatic studies to determine IC50 values and mechanism-of-action for tankyrase 1 and tankyrase 2.
• Academic Research: Fundamental research tool in universities and institutes for investigating chromosome stability, DNA damage response, and aging.

Basic Information

Product Name	Taps
CAS No.	29915-38-6
Molecular Formula	C₁₃H₁₀N₄O₂
Molecular Weight	254.24 g/mol
Synonyms	3-(1,3-Dihydro-1,3-dioxo-2H-isoindol-2-yl)-N-(4-pyridinylmethyl)benzamide; TANKYRASE Inhibitor; XAV939; Tankyrase 1/2 Inhibitor XAV939; 3-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-N-(pyridin-4-ylmethyl)benzamide; N-(Pyridin-4-ylmethyl)-3-(phthalimid-1-yl)benzamide; Benzamide, 3-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-N-(4-pyridinylmethyl)-
EINECS	Contact for details

Quality Control

Our Taps (CAS 29915-38-6) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards, and specifications can be tailored to meet specific research-grade or preclinical-grade requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This compound is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a desiccator before opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Solubility	Soluble in DMSO, DMF; slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.