Description

2-(n-Morpholino)Ethanesulfonic Acid Hemisodium Salt is a high-purity biochemical buffer salt, essential for maintaining precise pH stability in sensitive biological and chemical systems. Its primary value lies in its excellent buffering capacity in the pH range of 5.5-6.7, making it a critical component for research and manufacturing processes requiring consistent ionic conditions. This product is vital for biopharmaceutical development, molecular biology research, and diagnostic reagent formulation, where even minor pH fluctuations can compromise results or product integrity.

Application

• Biopharmaceutical Buffer: Used in cell culture media, fermentation processes, and as a component in the purification and formulation of therapeutic proteins, vaccines, and monoclonal antibodies.
• Molecular Biology Reagent: Serves as a key buffering agent in nucleic acid extraction kits, PCR master mixes, electrophoresis running buffers, and enzyme reaction systems.
• Diagnostic Manufacturing: Incorporated into the formulation of clinical diagnostic kits, assay buffers, and calibration standards to ensure accuracy and reproducibility.
• Biochemical Research: Provides a stable pH environment for in vitro enzymatic studies, protein crystallization, and tissue culture applications.
• Chromatography: Used in the mobile phase for ion-exchange and affinity chromatography to separate and purify biomolecules.

Basic Information

Product Name	2-(n-Morpholino)Ethanesulfonic Acid Hemisodium Salt
CAS No.	117961-21-4
Molecular Formula	C6H12NNaO4S
Molecular Weight	217.22 g/mol
Synonyms	MES Hemisodium Salt; 2-(4-Morpholino)ethanesulfonic Acid Hemisodium Salt; 4-Morpholineethanesulfonic Acid Hemisodium Salt; MES Sodium Salt (hemi); Sodium 2-(morpholin-4-yl)ethanesulfonate (1:1); Sodium MES (hemi); MES Monosodium Salt; Sodium 4-morpholineethanesulfonate
EINECS	Contact for details

Quality Control

Our 2-(n-Morpholino)Ethanesulfonic Acid Hemisodium Salt is manufactured under a cGMP-compliant quality management system to ensure batch-to-batch consistency and traceability. Each lot undergoes rigorous analytical testing, including HPLC for purity, titration for assay, and stringent limits for endotoxins and bioburden where applicable. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (Titration)	98.0% - 102.0%
pH (1% Solution)	5.5 - 6.5
Loss on Drying	≤ 1.0%
Heavy Metals (as Pb)	≤ 10 ppm
Endotoxin (where specified)	< 0.25 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.