Description

(2S,5R,6R)-6-[[(2R)-2-amino-2-phenyl-acetyl]amino]-3,3-dimethyl-7-oxo- 4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid: (2S,5R,6R)-3,3-di methyl-6-[(5-methyl-3-phenyl-oxazole-4-carbonyl)amino]-7-oxo-4-thia-1- azabicyclo[3.2.0]heptane-2-carboxylic acid is a high-purity, semi-synthetic chemical compound of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard for the synthesis and analysis of novel β-lactam structures. It is primarily required by pharmaceutical manufacturers, contract research organizations (CROs), and analytical laboratories engaged in the development of new therapeutic agents, particularly in the antibiotic and antimicrobial space.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel β-lactam antibiotics and related active pharmaceutical ingredients (APIs).
• Research & Development: Used as a reference standard or starting material in medicinal chemistry programs targeting bacterial infections.
• Analytical Standard: Serves as a high-purity certified reference material (CRM) for method development, validation, and quality control testing in HPLC, LC-MS, and NMR.
• Process Chemistry: Employed in route scouting and optimization studies for the scalable production of specialized pharmaceutical compounds.
• Academic Research: Utilized in university and institutional labs for studying structure-activity relationships (SAR) and mechanisms of action within the β-lactam class.

Basic Information

Product Name	(2S,5R,6R)-6-[[(2R)-2-amino-2-phenyl-acetyl]amino]-3,3-dimethyl-7-oxo- 4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid: (2S,5R,6R)-3,3-di methyl-6-[(5-methyl-3-phenyl-oxazole-4-carbonyl)amino]-7-oxo-4-thia-1- azabicyclo[3.2.0]heptane-2-carboxylic acid
CAS No.	8067-85-4
Molecular Formula	C26H26N4O6S
Molecular Weight	522.58 g/mol
Synonyms	6-[(Aminophenylacetyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; 6-[(5-Methyl-3-phenyl-4-isoxazolecarboxamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; Ampicillin Oxazole Derivative; β-lactam Oxazole Intermediate; (2S,5R,6R)-6-[(2R)-2-Amino-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid oxazole analog; CAS 8067-85-4
EINECS	Contact for details

Quality Control

Our production of this advanced pharmaceutical intermediate adheres to strict quality management systems. Each batch is subjected to comprehensive analytical characterization using techniques including HPLC, NMR, and MS to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting critical parameters such as assay, related substances, and residual solvents. We support development and commercial projects requiring compliance with ICH Q7 and cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled in a dry environment to maintain stability and purity. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.