Description

Oxacillin Sodium is a semi-synthetic penicillinase-resistant β-lactam antibiotic. It is valued for its stability against staphylococcal penicillinase, making it a critical agent for treating infections caused by penicillin-resistant bacteria. This active pharmaceutical ingredient (API) is essential for manufacturers in the pharmaceutical industry, particularly for formulating injectable and oral antibiotic preparations.

Application

• Pharmaceutical API: Primary use as the active ingredient in injectable and oral antibiotic formulations.
• Treatment of Resistant Infections: Specifically indicated for infections caused by penicillinase-producing staphylococci.
• Hospital & Clinical Use: Formulated for intravenous or intramuscular administration in hospital settings for severe infections.
• Veterinary Medicine: Used in certain veterinary antibiotic preparations for bacterial infections in animals.
• Research & Development: Serves as a reference standard and key intermediate in antimicrobial research and new drug development.
• Bacteriological Studies: Utilized in microbiological laboratories for susceptibility testing and studies on bacterial resistance mechanisms.

Basic Information

Product Name	Oxacillin Sodium
CAS No.	1173-88-2
Molecular Formula	C19H18N3NaO5S
Molecular Weight	423.42 g/mol
Synonyms	Oxacillin Sodium Salt; Sodium Oxacillin; (2S,5R,6R)-3,3-Dimethyl-6-[[(5-methyl-3-phenyl-1,2-oxazol-4-yl)carbonyl]amino]-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid sodium salt; Bactocill; Prostaphlin; P-12; BRL-1400; Methocillin-S
EINECS	214-606-7

Quality Control

Our Oxacillin Sodium is manufactured and tested to meet high-purity standards suitable for pharmaceutical applications. Quality is assured through a comprehensive battery of tests including identification, assay, and impurity profiling. Certificates of Analysis (COA) are provided with each batch, detailing compliance with relevant specifications. We support compliance with cGMP and major pharmacopoeial standards (USP, EP, BP) upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic nature, the container must be kept tightly sealed to protect from moisture. Recommended long-term storage temperature is 2°C to 8°C (refrigerated). For short-term or in-use storage, keep at controlled room temperature (15-25°C).

Specification

Item	Specification
Appearance	White to almost white crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	97.0% - 102.0% (on anhydrous basis)
pH (10% solution)	5.0 - 7.0
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%
Bacterial Endotoxins	< 0.25 IU/mg (where applicable)
Sterility (for sterile grade)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.