Description

Penicillin, Calcium Salt is a critical pharmaceutical-grade intermediate derived from the penicillin class of β-lactam antibiotics. This compound is essential for its role in the synthesis and formulation of various antibiotic preparations, ensuring therapeutic efficacy and stability. It is primarily utilized by manufacturers in the pharmaceutical, veterinary medicine, and advanced research sectors for producing injectable and oral antibiotic formulations.

Application

• Pharmaceutical API Synthesis: A key starting material or intermediate in the production of various penicillin-based active pharmaceutical ingredients (APIs).
• Veterinary Medicine: Used in the formulation of antibiotics for the treatment of bacterial infections in livestock and companion animals.
• Research & Development: Serves as a standard or reagent in microbiological assays and biochemical research focused on antibiotic mechanisms and resistance.
• Sterile Injectable Formulations: Employed in the manufacture of calcium penicillin G for intramuscular or intravenous administration.
• Oral Dosage Forms: A component in the production of certain oral antibiotic preparations, often requiring specific salt forms for stability and bioavailability.

Basic Information

Product Name	Penicillin, Calcium Salt
CAS No.	1406-07-1
Molecular Formula	C16H18CaN2O4S2
Molecular Weight	406.53 g/mol
Synonyms	Calcium Penicillin G; Penicillin G Calcium Salt; Benzylpenicillin Calcium Salt; Calcium Benzylpenicillin; (2S,5R,6R)-3,3-Dimethyl-7-oxo-6-[(phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid calcium salt; Crystalline Penicillin G Calcium; Calcium (2S,5R,6R)-3,3-dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
EINECS	215-785-8

Quality Control

Our Penicillin, Calcium Salt is manufactured under strict quality management systems. Each batch is tested to ensure it meets high-purity standards suitable for pharmaceutical applications, with specifications potentially aligned with relevant pharmacopoeial monographs. Certificates of Analysis (COA) documenting identity, purity, and related substances are provided to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term stability, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Assay (HPLC)	≥ 96.0% (anhydrous basis)
Water (KF)	≤ 3.0%
pH (aqueous solution)	5.0 - 7.5
Specific Rotation	+280° to +310°

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.