Description

Penicillin V Potassium Salt is a semi-synthetic, β-lactam antibiotic derived from phenoxymethylpenicillin. This compound is valued for its acid stability, allowing for effective oral administration, and its potent bactericidal activity against a range of Gram-positive organisms. It is a critical active pharmaceutical ingredient (API) for manufacturers in the pharmaceutical industry, primarily used in the formulation of oral antibiotic medications. Penicillin V Potassium Salt CAS NO 132-98-9 is essential for producing reliable and effective treatments for common bacterial infections.

Application

• Pharmaceutical API: Primary use as the active ingredient in oral antibiotic tablets, capsules, and powders.
• Veterinary Medicine: Formulation of antibacterial treatments for livestock and companion animals.
• Clinical Research: Used as a reference standard and in studies related to antibiotic efficacy and resistance.
• Bacteriological Media: Selective agent in laboratory culture media for microbiological testing.
• Intermediate Synthesis: Serves as a starting material or intermediate for further chemical synthesis of other penicillin derivatives.

Basic Information

Product Name	Penicillin V Potassium Salt
CAS No.	132-98-9
Molecular Formula	C16H17KN2O5S
Molecular Weight	388.48 g/mol
Synonyms	Phenoxymethylpenicillin Potassium; Penicillin VK; Potassium Penicillin V; (2S,5R,6R)-3,3-Dimethyl-7-oxo-6-[(2-phenoxyacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid potassium salt; 6-Phenoxyacetamidopenicillanic acid potassium salt; Abbocillin-VK; V-Cillin K; Ledercillin VK
EINECS	205-099-1

Quality Control

Our Penicillin V Potassium Salt is manufactured and tested to meet stringent pharmacopeial standards, including USP and EP monographs. Every batch undergoes comprehensive analytical testing for identity, potency, purity, and specified impurities. A Certificate of Analysis (COA) detailing results for assay, water content, related substances, and microbiological quality is provided to ensure full traceability and compliance with cGMP guidelines for pharmaceutical ingredients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term stability, consider storage under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	95.0% - 102.0% (on anhydrous basis)
Water (Karl Fischer)	≤ 1.5%
pH (5% solution)	5.0 - 7.5
Specific Optical Rotation	+223° to +237°
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents	Complies with ICH Q3C
Heavy Metals	≤ 20 ppm
Microbial Enumeration	Complies with EP/USP

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.