Description

Penicillin V Sodium is the sodium salt of Penicillin V, a narrow-spectrum, acid-stable antibiotic belonging to the β-lactam class. This compound is critical for its reliable efficacy against Gram-positive bacteria, particularly in oral formulations where its stability in acidic environments is a key advantage. It is an essential active pharmaceutical ingredient (API) for manufacturers in the pharmaceutical industry, primarily used in the production of oral antibiotic medications to treat infections such as streptococcal pharyngitis and skin infections.

Application

• Pharmaceutical API: Primary use as the active ingredient in oral antibiotic tablets, capsules, and oral suspensions.
• Veterinary Medicine: Formulation of antibiotics for treating bacterial infections in animals.
• Research & Development: Used as a reference standard and in microbiological research for studying antibiotic resistance and efficacy.
• Bulk Drug Substance: Sourced by contract manufacturing organizations (CMOs) for finished dosage form production.
• Compounding Pharmacy: Utilized in specialized pharmacy compounding for tailored patient medications.

Basic Information

Product Name	Penicillin V Sodium
CAS No.	1098-87-9
Molecular Formula	C16H17N2NaO5S
Molecular Weight	372.37 g/mol
Synonyms	Phenoxymethylpenicillin Sodium Salt; Penicillin V Sodium Salt; Phenethicillin Sodium; (2S,5R,6R)-3,3-Dimethyl-7-oxo-6-[(2-phenoxyacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid sodium salt; Potassium Penicillin V (related salt); Pen V Na; PVS; EINECS 214-155-7
EINECS	214-155-7

Quality Control

Our Penicillin V Sodium is manufactured under strict quality systems. It is typically tested for compliance with major pharmacopeial standards such as USP (United States Pharmacopeia) and EP (European Pharmacopoeia). Each batch undergoes rigorous analytical testing including assay, impurity profiling, and microbiological examination. A comprehensive Certificate of Analysis (COA) documenting purity, potency, and conformance to specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	96.0% - 102.0% (on anhydrous basis)
pH (1% Solution)	5.0 - 7.5
Water (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C
Microbial Enumeration	Complies with EP/USP

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.