Description

Penicillin G Potassium Salt is the potassium salt of benzylpenicillin, a fundamental β-lactam antibiotic. It is a critical active pharmaceutical ingredient (API) and intermediate for the production of various antibiotic formulations. This high-purity compound is essential for pharmaceutical manufacturers, research institutions, and veterinary medicine producers requiring a reliable and consistent source for antibiotic development and production.

Application

• Pharmaceutical API: Primary use as the active ingredient in injectable antibiotic formulations for human and veterinary use.
• Research & Development: A key reference standard and starting material in microbiological research and the development of new antibiotic derivatives.
• Veterinary Medicine: Used in the manufacture of treatments for bacterial infections in livestock and companion animals.
• Cell Culture: Employed in selective media to prevent bacterial contamination in biotechnological and cell culture applications.
• Intermediate Synthesis: Serves as a crucial precursor in the chemical synthesis of semi-synthetic penicillins.

Basic Information

Product Name	Penicillin G Potassium Salt
CAS No.	113-98-4
Molecular Formula	C16H17KN2O4S
Molecular Weight	372.48 g/mol
Synonyms	Benzylpenicillin Potassium; Potassium Benzylpenicillin; Penicillin G K Salt; Benzylpenicillin Potassium Salt; (2S,5R,6R)-3,3-Dimethyl-7-oxo-6-[(phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid potassium salt; Crystalline Penicillin G Potassium; Potassium Penicillin G
EINECS	204-038-8

Quality Control

Our Penicillin G Potassium Salt is manufactured and tested under strict quality management systems. It meets high-purity standards suitable for pharmaceutical applications, with specifications typically aligned with major pharmacopoeial guidelines. A comprehensive Certificate of Analysis (COA) detailing identity, potency, purity, and related substances is provided with each batch to ensure traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	96.0% - 102.0% (on anhydrous basis)
pH (Solution)	5.0 - 7.5
Water (Karl Fischer)	≤ 1.0%
Specific Optical Rotation	+285° to +310°

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.