Description

Quinacillin CAS NO 1596-63-0 is a semisynthetic penicillin antibiotic known for its activity against Gram-negative bacteria. Its primary commercial value lies in its role as a key intermediate in the synthesis of more complex β-lactam antibiotics and as a reference standard for analytical and research purposes. This compound is essential for pharmaceutical R&D laboratories, manufacturers of active pharmaceutical ingredients (APIs), and quality control facilities requiring high-purity chemical standards.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of advanced penicillin derivatives and other β-lactam antibiotics.
• Analytical Reference Standard: Used for method development, validation, and quality control testing in pharmaceutical analysis via HPLC, LC-MS, or other chromatographic techniques.
• Microbiological Research: Employed in studies investigating bacterial resistance mechanisms, antibiotic efficacy, and structure-activity relationships (SAR) of β-lactam compounds.
• API Manufacturing: Serves as a starting material or intermediate in the controlled production of antibiotic active pharmaceutical ingredients under GMP conditions.
• Biochemical Studies: Utilized in enzymatic assays to study the interaction with penicillin-binding proteins (PBPs) and β-lactamases.

Basic Information

Item	Detail
Product Name	Quinacillin
CAS No.	1596-63-0
Molecular Formula	C19H23N3O5S
Molecular Weight	405.47 g/mol
Synonyms	Quinacillin; Quinacillin Sodium; 6-[D-α-(3-Carboxy-2-quinoxalinylcarbonylamino)phenylacetamido]penicillanic Acid; 6-[(Carboxy-2-quinoxalinylcarbonylamino)phenylacetamido]penicillanic Acid; Quinacillinum; Quinacillinum [INN-Latin]; CL-86,233; Antibiotic CL 86,233; Sodium Quinacillin
EINECS	Contact for details

Quality Control

Our Quinacillin is produced and tested to meet stringent quality standards suitable for research and pharmaceutical applications. Every batch undergoes comprehensive analysis including identification, purity assay, and impurity profiling. Certificates of Analysis (COA) documenting results for appearance, assay (HPLC), related substances, water content, and residual solvents are provided to ensure traceability and compliance. We support GMP and ISO guided manufacturing principles for consistent quality and supply reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.