Description

Sodium [2S-[2alpha,5alpha,6beta(S*)]]-6-[[[(3-methoxy-1-methyl-3-oxoprop-1-enyl)amino]phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate is a high-purity sodium salt derivative of a penicillin-based structure, serving as a critical pharmaceutical intermediate. This compound is essential for the synthesis and research of advanced β-lactam antibiotics, offering a reliable building block for medicinal chemistry. It is primarily required by pharmaceutical manufacturers, R&D laboratories, and fine chemical producers focused on developing novel antibacterial agents and conducting pharmacological studies.

Application

• Pharmaceutical Intermediate: Key starting material or intermediate in the synthesis of novel penicillin and β-lactam antibiotic derivatives.
• Antibacterial Research: Used in research and development to study structure-activity relationships (SAR) and develop new antimicrobial agents.
• Medicinal Chemistry: Serves as a crucial scaffold for the modification and creation of new chemical entities (NCEs) with potential therapeutic value.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Studies: Utilized in biochemical assays to investigate bacterial cell wall synthesis and inhibition mechanisms.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for producing specialized, high-value chemical products.

Basic Information

Product Name	Sodium [2S-[2alpha,5alpha,6beta(S*)]]-6-[[[(3-methoxy-1-methyl-3-oxoprop-1-enyl)amino]phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
CAS No.	64099-47-4
Molecular Formula	C24H26N3NaO7S
Molecular Weight	523.54 g/mol
Synonyms	Sodium 6-[(2,2-Dimethyl-5-oxo-4-phenyl-1-imidazolidinyl)carbonyl]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate; Sodium (2S,5R,6R)-6-[(2,2-Dimethyl-5-oxo-4-phenyl-1-imidazolidinyl)carbonyl]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate; Sodium 6-APA derivative; Sodium penicillin intermediate; Sodium salt of 6-[(phenylacetyl)amino]penicillanic acid derivative; BLI-489 sodium salt (related compound)
EINECS	Contact for details

Quality Control

Our sodium penicillin intermediate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards for pharmaceutical research and synthesis. Certificates of Analysis (COA) with detailed specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.