Description

4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[[[(2,3-dihydro-4-methyl-3-oxo-1H-pyrazol-1-yl)carbonyl]amino]phenylacetyl]amino]-3,3-dimethyl-7-oxo-, monosodium salt, [2S-[2alpha,5alpha,6beta(S*)]]- is a high-purity monosodium salt derivative of a complex penicillin-like structure, serving as a critical pharmaceutical intermediate or reference standard. Its primary value lies in enabling the research and development of novel β-lactam compounds and advanced antibiotic formulations. This product is essential for pharmaceutical manufacturers and research institutions focused on antimicrobial drug discovery and quality control.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of advanced β-lactam antibiotics and related therapeutic agents.
• Reference Standard: Used for analytical method development, validation, and quality control (QC) testing in pharmaceutical laboratories.
• Antimicrobial Research: Serves as a precursor or model compound in the research of new antibacterial mechanisms and resistance studies.
• Process Chemistry: Employed in the development and scale-up of synthetic routes for complex pharmaceutical active ingredients (APIs).
• Impurity Profiling: Utilized as a known impurity or degradation product standard to ensure the purity and safety of final drug substances.

Basic Information

Product Name	4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[[[(2,3-dihydro-4-methyl-3-oxo-1H-pyrazol-1-yl)carbonyl]amino]phenylacetyl]amino]-3,3-dimethyl-7-oxo-, monosodium salt, [2S-[2alpha,5alpha,6beta(S*)]]-
CAS No.	54944-56-8
Molecular Formula	C22H23N5NaO7S
Molecular Weight	516.50 g/mol
Synonyms	Sodium 6-[D-α-(4-methyl-3-oxo-1-pyrazoline-1-carboxamido)phenylacetamido]penicillanate; Sodium 6-[2-(3-carbamoyl-4-methylpyrazol-1-yl)-2-phenylacetamido]penicillanate; 6-APA derivative monosodium salt; Penicillin G pyrazolone derivative sodium salt; (2S,5R,6R)-3,3-Dimethyl-7-oxo-6-[(R)-2-phenyl-2-[(4-methyl-3-oxo-1-pyrazoline-1-carboxamido)]acetamido]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid sodium salt; A related penicillin intermediate sodium salt.
EINECS	Contact for details

Quality Control

Our high-purity pharmaceutical intermediate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications for research and production use. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.