Description

4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-6-[[[[[3-(methylsulfonyl)-2-oxo-1-imidazolidinyl]carbonyl]amino]phenylacetyl]amino]-7-oxo-, monosodium salt, [2S-[2alpha,5alpha,6beta(S*)]]- is a high-purity, semi-synthetic β-lactam compound of significant pharmaceutical interest. This advanced intermediate is critical for the synthesis of novel and potent broad-spectrum antibiotics, offering a key building block for modern antimicrobial research and development. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in the development of next-generation antibacterial agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of advanced cephalosporin and penem class antibiotics.
• Antibacterial Drug Development: Used in research for creating new agents with activity against resistant bacterial strains.
• Fine Chemical Synthesis: Serves as a specialized building block for constructing complex molecular architectures in medicinal chemistry.
• Biochemical Research: Employed in studies investigating the mechanism of action and structure-activity relationships (SAR) of β-lactam antibiotics.
• GMP Manufacturing: Suitable for use in cGMP-compliant processes for the production of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-6-[[[[[3-(methylsulfonyl)-2-oxo-1-imidazolidinyl]carbonyl]amino]phenylacetyl]amino]-7-oxo-, monosodium salt, [2S-[2alpha,5alpha,6beta(S*)]]-
CAS No.	42057-22-7
Molecular Formula	C22H26N5NaO8S2
Molecular Weight	591.59 g/mol
Synonyms	Sodium (6R,7R)-7-[[(2R)-2-[[[3-(Methylsulfonyl)-2-oxoimidazolidine-1-carbonyl]amino]-2-phenylacetyl]amino]-3,3-dimethyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate; Sodium 7β-[[(R)-2-[[[3-(Methylsulfonyl)-2-oxoimidazolidin-1-yl]carbonyl]amino]-2-phenylacetamido]-3,3-dimethyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate; Cefsulodin Sodium Impurity; Cefsulodin Related Compound A; Cefsulodin EP Impurity A; Cefsulodin Sodium Salt Impurity; Antibiotic FR 10612 Sodium Salt; FR-10612 Sodium Salt
EINECS	Contact for details

Quality Control

Our 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-6-[[[[[3-(methylsulfonyl)-2-oxo-1-imidazolidinyl]carbonyl]amino]phenylacetyl]amino]-7-oxo-, monosodium salt is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance with pharmaceutical development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.