Description

Potassium [2S-[2alpha,5alpha,6beta(S*)]]-6-[[[(3-methoxy-1-methyl-3-oxoprop-1-enyl)amino]phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate is a potassium salt derivative of a complex penicillin core structure, serving as a critical advanced pharmaceutical intermediate. This compound is essential for the synthesis of high-value, semi-synthetic β-lactam antibiotics, enabling precise chemical modifications to enhance drug efficacy and stability. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development and production of next-generation antibacterial agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel penicillin and cephalosporin-class antibiotics.
• Antibacterial Drug Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies to develop new antimicrobial agents.
• Active Pharmaceutical Ingredient (API) Synthesis: Employed in the final chemical steps to produce potassium salt forms of specific β-lactam antibiotics.
• Process Chemistry & Scale-Up: Serves as a standardized intermediate for process optimization and pilot-scale manufacturing in GMP environments.
• Reference Standard: Can be utilized as an analytical standard for quality control and regulatory filing purposes.

Basic Information

Item	Details
Product Name	Potassium [2S-[2alpha,5alpha,6beta(S*)]]-6-[[[(3-methoxy-1-methyl-3-oxoprop-1-enyl)amino]phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
CAS No.	40126-27-0
Molecular Formula	C24H28KN3O7S
Molecular Weight	541.66 g/mol
Synonyms	Potassium 6-[(2S)-2-[[(2Z)-3-Methoxy-1-methyl-3-oxoprop-1-en-1-yl]amino]-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate; Potassium (2S,5R,6R)-6-[(2S)-2-[[(2Z)-3-Methoxy-1-methyl-3-oxoprop-1-en-1-yl]amino]-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate; Potassium Penicillin G Derivative; Potassium salt of methoxy-substituted penicillin intermediate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for pharmaceutical intermediates. We adhere to strict in-process controls and final release specifications, which typically include identity confirmation, purity assay, and related substance analysis. Certificates of Analysis (COA) detailing batch-specific results are available upon request. Production can be aligned with GMP guidelines for applications requiring higher regulatory scrutiny.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Potassium Content (Titration)	Conforms to theoretical range

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.