Description

[2S-[2alpha,5alpha,6beta(S*)]]-6-[(aminophenylacetyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid mono(hydroxymethoxybenzenesulphonate) is a key pharmaceutical intermediate and derivative of the β-lactam antibiotic class. This compound is of significant importance for its role in the synthesis and research of advanced antibacterial agents. It is primarily required by manufacturers and research institutions in the pharmaceutical and fine chemical sectors engaged in antibiotic development and production.

Application

• Active Pharmaceutical Ingredient (API) Intermediate: A critical building block in the synthesis of semi-synthetic penicillin and cephalosporin antibiotics.
• Pharmaceutical Research & Development: Used in medicinal chemistry for the discovery and structural modification of new antibacterial compounds.
• Reference Standard: Serves as a high-purity analytical standard for quality control and regulatory testing in pharmaceutical manufacturing.
• Biochemical Research: Employed in studies investigating bacterial cell wall synthesis and the mechanisms of β-lactamase inhibition.
• Fine Chemical Synthesis: Utilized as a specialized chiral synthon for constructing complex molecular architectures in advanced organic synthesis.

Basic Information

Product Name	[2S-[2alpha,5alpha,6beta(S*)]]-6-[(aminophenylacetyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid mono(hydroxymethoxybenzenesulphonate)
CAS No.	39050-96-9
Molecular Formula	C23H27N3O9S2
Molecular Weight	553.61 g/mol
Synonyms	6-APA Sulfonate Derivative; Ampicillin Sulfonate Intermediate; (2S,5R,6R)-6-[(R)-2-Amino-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid compound with 4-(hydroxymethoxy)benzenesulfonic acid; Ampicillin sulfonate; D-(-)-α-Aminobenzylpenicillin sulfonate; Benzenesulfonic acid, 4-(hydroxymethoxy)-, compd. with (2S,5R,6R)-6-[(R)-2-amino-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid (1:1)
EINECS	Contact for details

Quality Control

Our [2S-[2alpha,5alpha,6beta(S*)]]-6-[(aminophenylacetyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid mono(hydroxymethoxybenzenesulphonate) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) documenting all critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Recommended long-term storage at controlled room temperature (15-25°C).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.