Description

4,8-Dioxa-12,16-diazaheneicosanamide, 6-amino-11,17-dioxo-6-[[3-oxo-3-[[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]amino]propoxy]methyl]-N-[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]-21-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-, 2,2,2-trifluoroacetate (1:1) is a sophisticated, high-purity synthetic intermediate characterized by its complex, multi-functional structure incorporating protected galactosamine moieties. This compound is of critical importance for advanced research and development in bioconjugation and glycobiology, serving as a key building block for creating targeted probes and therapeutics. It is primarily needed by pharmaceutical R&D teams, biotechnology companies, and academic research institutions focused on developing novel drug delivery systems, diagnostic agents, and carbohydrate-based vaccines.

Application

• Bioconjugation Reagent: Used for the site-specific modification of proteins, antibodies, and peptides to introduce galactose-derived targeting ligands.
• Glycobiology Research: Serves as a critical intermediate in the synthesis of complex oligosaccharides, glycopeptides, and glycomimetics for studying carbohydrate-protein interactions.
• Drug Delivery System Development: A key component in the design of targeted prodrugs and nanocarriers that exploit lectin-mediated uptake pathways, such as the asialoglycoprotein receptor (ASGPR).
• Diagnostic Probe Synthesis: Utilized in the creation of molecular imaging probes and contrast agents for detecting specific biological targets.
• Pharmaceutical Intermediate: An essential building block in the multi-step synthesis of novel active pharmaceutical ingredients (APIs) with enhanced targeting properties.
• Biomaterial Functionalization: Employed to modify surfaces of polymers, nanoparticles, and hydrogels with bioactive carbohydrate motifs to improve biocompatibility and cell-specific interactions.

Basic Information

Item	Details
Product Name	4,8-Dioxa-12,16-diazaheneicosanamide, 6-amino-11,17-dioxo-6-[[3-oxo-3-[[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]amino]propoxy]methyl]-N-[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]-21-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-, 2,2,2-trifluoroacetate (1:1)
CAS No.	1159408-65-7
Molecular Formula	C66H108F3N9O30
Molecular Weight	~1620.6 g/mol (Contact for exact details)
Synonyms	Galactosamine-based Trivalent Bioconjugation Linker; TFA Salt of a Tri-GalNAc Spacer; N-Acetylgalactosamine (GalNAc) Trimer Conjugation Reagent; Triantennary GalNAc Cluster Intermediate; ASGPR-Targeting Ligand Precursor; Glycosylated Polyamide Linker TFA Salt; 6-Amino-6-[[3-oxo-3-[[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]amino]propoxy]methyl]-N-[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]-4,8-dioxa-12,16-diazaheneicosanamide-11,17-dione-21-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy] 2,2,2-trifluoroacetate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for advanced research chemicals. Every batch is characterized using advanced analytical techniques including HPLC, NMR, and Mass Spectrometry to confirm identity, purity, and structural integrity. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are available upon request. We adhere to strict in-house quality protocols suitable for pharmaceutical R&D applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize condensation and moisture uptake. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.