Description

1,5-Anhydro-4-O-[3,4-O-carbonyl-6-O-[(1,1-dimethylethyl)diphenylsilyl]-β-D-galactopyranosyl]-2-deoxy-6-O-[(1,1-dimethylethyl)diphenylsilyl]-D-arabino-hex-1-enitol is a sophisticated, high-purity synthetic intermediate featuring dual tert-butyldiphenylsilyl (TBDPS) protecting groups and a cyclic carbonate moiety. This compound matters as a critical building block for the controlled synthesis of complex oligosaccharides and glycoconjugates, offering precise reactivity for advanced glycosylation strategies. It is primarily needed by research institutions and pharmaceutical developers working on carbohydrate-based drug discovery, vaccine development, and the synthesis of biologically active natural products.

Application

• Advanced Glycosylation Chemistry: Serves as a key, protected donor/acceptor molecule in the stereoselective synthesis of complex oligosaccharide chains.
• Pharmaceutical Intermediate: Used in the research and development of novel carbohydrate-based therapeutics, including antiviral and anticancer agents.
• Glycoconjugate Synthesis: A pivotal precursor for creating glycoproteins, glycolipids, and other conjugates for immunological and diagnostic applications.
• Chemical Biology Probes: Employed in the construction of labeled sugar analogs for studying carbohydrate-processing enzymes and metabolic pathways.
• Process Development: Supports route scouting and optimization for the scalable production of high-value carbohydrate active pharmaceutical ingredients (APIs).
• Academic & Industrial R&D: A valuable tool for synthetic organic chemists in both university laboratories and industrial R&D departments focused on glycoscience.

Basic Information

Item	Details
Product Name	1,5-Anhydro-4-O-[3,4-O-carbonyl-6-O-[(1,1-dimethylethyl)diphenylsilyl]-β-D-galactopyranosyl]-2-deoxy-6-O-[(1,1-dimethylethyl)diphenylsilyl]-D-arabino-hex-1-enitol
CAS No.	159494-36-7
Molecular Formula	C48H58O10Si2
Molecular Weight	851.15 g/mol
Synonyms	1,5-Anhydro-4-O-[3,4-O-carbonyl-6-O-(tert-butyldiphenylsilyl)-β-D-galactopyranosyl]-2-deoxy-6-O-(tert-butyldiphenylsilyl)-D-arabino-hex-1-enitol; TBDPS-protected galactosyl carbonate derivative; 1,5-Anhydro-2-deoxy-4-O-[3,4-O-carbonyl-6-O-[(1,1-dimethylethyl)diphenylsilyl]-β-D-galactopyranosyl]-6-O-[(1,1-dimethylethyl)diphenylsilyl]-D-arabino-hex-1-enitol; Bis-TBDPS galactose carbonate intermediate; CAS 159494-36-7
EINECS	Contact for details

Quality Control

Our 1,5-Anhydro-4-O-[3,4-O-carbonyl-6-O-[(1,1-dimethylethyl)diphenylsilyl]-β-D-galactopyranosyl]-2-deoxy-6-O-[(1,1-dimethylethyl)diphenylsilyl]-D-arabino-hex-1-enitol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with exacting research and development standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This compound is sensitive to fluoride and strong alkali; ensure it is stored separately from such reagents. For long-term storage under inert atmosphere is recommended to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.