Description

(E)-3-(4-Fluoro-Phenyl)-But-2-Enoic Acid CAS NO 1201-86-1 is a high-purity, fluorinated organic acid derivative characterized by its specific stereochemistry and phenyl ring substitution. This compound serves as a versatile and critical pharmaceutical intermediate and building block in advanced organic synthesis. It is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and inflammatory conditions.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and fungicides, leveraging the bioactivity of the fluorophenyl moiety.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic displays and optoelectronic devices.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, such as Heck reactions, and for introducing the (E)-3-arylbut-2-enoic acid scaffold into more complex molecules.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D focused on medicinal chemistry, material science, and novel synthetic methodologies.

Basic Information

Product Name	(E)-3-(4-Fluoro-Phenyl)-But-2-Enoic Acid
CAS No.	1201-86-1
Molecular Formula	C10H9FO2
Molecular Weight	180.18 g/mol
Synonyms	(E)-3-(4-Fluorophenyl)but-2-enoic acid; trans-3-(4-Fluorophenyl)-2-butenoic acid; (E)-3-(p-Fluorophenyl)crotonic acid; 4-Fluoro-β-methylcinnamic acid; (2E)-3-(4-Fluorophenyl)but-2-enoic Acid; 1201-86-1; (E)-3-(4-Fluorophenyl)-2-butenoic Acid; p-Fluoro-β-methylcinnamic acid
EINECS	Contact for details

Quality Control

Our (E)-3-(4-Fluoro-Phenyl)-But-2-Enoic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available upon request, detailing all specified parameters to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong bases, oxidizing agents, and heat sources.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.