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2-Fluorobenzoic Acid CAS NO 445-29-4


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CAS No.:445-29-4

Grade:Pharmacy Grade

Content:99.0%

Brand:Customizable

Packaging:Customizable

Description

2-Fluorobenzoic Acid is a versatile fluorinated aromatic carboxylic acid serving as a critical building block in advanced organic synthesis. Its value lies in the unique reactivity imparted by the fluorine atom, which is strategically used to modulate the electronic and steric properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, where it is employed to develop novel active ingredients and functional materials.

Application

  • Pharmaceutical Intermediate: A key synthon for the preparation of fluorinated active pharmaceutical ingredients (APIs), including potential anti-inflammatory and antimicrobial agents.
  • Agrochemical Synthesis: Used in the research and production of advanced herbicides, pesticides, and fungicides, where the fluorine atom enhances biological activity and stability.
  • Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic cores used in electronic display technologies.
  • Polymer Modification: Incorporated into polymer chains to alter thermal stability, chemical resistance, and surface properties of specialty plastics and coatings.
  • Organic Synthesis Reagent: Utilized in various coupling reactions (e.g., Suzuki, Heck) and as a protecting group or directing agent in complex molecule construction.
  • Fluorine Chemistry Research: A fundamental compound for studying structure-activity relationships (SAR) and the effects of fluorine substitution in medicinal and material chemistry.

Basic Information

Product Name 2-Fluorobenzoic Acid
CAS No. 445-29-4
Molecular Formula C7H5FO2
Molecular Weight 140.11 g/mol
Synonyms o-Fluorobenzoic Acid; 2-Fluorobenzenecarboxylic Acid; Benzoic acid, 2-fluoro-; o-Fluorodracylic Acid; FA; 2-FBA; Ortho-fluorobenzoic acid; USAF EK-5725
EINECS 207-158-4

Quality Control

Our 2-Fluorobenzoic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure it meets the high-purity standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and reducing agents.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Melting Point 122 - 126 °C
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals (as Pb) ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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