Description

3-Bromo-4-Fluorobenzoic Acid is a versatile halogenated benzoic acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic positioning of bromine and fluorine atoms on the aromatic ring, which allows for selective functionalization and the introduction of unique physicochemical properties into target molecules. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, where it is used to develop active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting new therapeutic agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the halogenated aromatic core contributes to biological activity.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated and brominated organic compounds used in electronic displays and optoelectronic devices.
• Polymer Modification: Incorporated into polymer chains to alter thermal stability, solubility, and other material properties for high-performance engineering plastics.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Heck, and Stille couplings for constructing complex biaryl systems.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new synthetic pathways and creating novel chemical entities.

Basic Information

Product Name	3-Bromo-4-Fluorobenzoic Acid
CAS No.	1007-16-5
Molecular Formula	C7H4BrFO2
Molecular Weight	219.01 g/mol
Synonyms	4-Fluoro-3-bromobenzoic Acid; 3-Bromo-4-fluorobenzoic Acid; Benzoic acid, 3-bromo-4-fluoro-; 1007-16-5; 3-Br-4-F-BA
EINECS	213-763-8

Quality Control

Our 3-Bromo-4-Fluorobenzoic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency meet the high standards required for synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	164 - 168 °C
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.