Description

2,4,5-Trifluoro-3-Methoxybenzoic Acid is a high-purity fluorinated aromatic building block essential for advanced organic synthesis. This compound is valued for its trifluoromethyl and methoxy substituents, which impart unique electronic and steric properties critical for modulating the bioactivity and physicochemical characteristics of target molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the design and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance metabolic stability and membrane permeability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated compounds for electronic applications, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Advanced Material Science: Employed in the development of specialty polymers, coatings, and functional materials that require specific fluorinated aromatic components.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and contract research organizations (CROs/CMOs) specializing in fluorochemistry.

Basic Information

Product Name	2,4,5-Trifluoro-3-Methoxybenzoic Acid
CAS No.	112811-65-1
Molecular Formula	C8H5F3O3
Molecular Weight	214.12 g/mol
Synonyms	3-Methoxy-2,4,5-trifluorobenzoic Acid; 2,4,5-Trifluoro-3-methoxybenzoic Acid; Benzoic acid, 2,4,5-trifluoro-3-methoxy-; 2,4,5-Trifluoro-m-anisic Acid
EINECS	Contact for details

Quality Control

Our 2,4,5-Trifluoro-3-Methoxybenzoic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.