Description

3-(2-Fluoro-Phenyl)-3-Oxo-Propionic Acid Ethyl Ester is a high-purity fluorinated organic building block essential for advanced chemical synthesis. This compound serves as a versatile intermediate, enabling the introduction of a 2-fluorophenyl ketone moiety into complex molecular architectures. It is primarily utilized by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated drug candidates, including potential CNS agents and anti-inflammatory compounds.
• Agrochemical Synthesis: Building block for developing novel fluorinated pesticides and herbicides, leveraging fluorine's ability to enhance bioavailability and metabolic stability.
• Material Science Research: Used in the development of specialty polymers and advanced organic materials with tailored electronic or photophysical properties.
• Chemical Research & Development: A fundamental reagent for method development in organic synthesis, particularly in cross-coupling and condensation reactions.
• Fluorine Chemistry Studies: Serves as a model compound for studying the influence of ortho-fluorine substitution on reaction kinetics and molecular conformation.

Basic Information

Product Name	3-(2-Fluoro-Phenyl)-3-Oxo-Propionic Acid Ethyl Ester
CAS No.	1479-24-9
Molecular Formula	C11H11FO3
Molecular Weight	210.20 g/mol
Synonyms	Ethyl 3-(2-fluorophenyl)-3-oxopropanoate; Ethyl 2-fluoro-β-oxobenzenepropanoate; 3-Oxo-3-(2-fluorophenyl)propionic acid ethyl ester; 2-Fluoro-β-oxohydrocinnamic acid ethyl ester; Ethyl (2-fluorobenzoyl)acetate; 2-Fluorobenzoylacetic acid ethyl ester; 1479-24-9; NSC 404080
EINECS	Contact for details

Quality Control

Our production of 3-(2-Fluoro-Phenyl)-3-Oxo-Propionic Acid Ethyl Ester adheres to stringent quality management protocols. Every batch is characterized and tested to ensure identity, purity, and consistency, meeting the exacting standards required for research and scale-up activities. A comprehensive Certificate of Analysis (COA) detailing purity (typically >97% by HPLC), physical characteristics, and impurity profiles is provided with each shipment to guarantee reliable and reproducible performance in your synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.