Description

2-Bromo-4-Fluorobenzoic Acid is a versatile halogenated benzoic acid derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both bromine and fluorine substituents, makes it a valuable intermediate for introducing specific steric and electronic properties into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic motifs.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and pesticides, where the fluorine and bromine atoms can enhance biological activity and stability.
• Liquid Crystal & OLED Materials: Serves as a building block for creating advanced organic electronic materials and liquid crystal compounds.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a starting material for more complex fluorinated and brominated compounds.
• Chemical Research & Development: A valuable tool in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Polymer Modification: Can be used to introduce functional groups into polymer chains to alter material properties.

Basic Information

Product Name	2-Bromo-4-Fluorobenzoic Acid
CAS No.	1006-41-3
Molecular Formula	C7H4BrFO2
Molecular Weight	219.01 g/mol
Synonyms	4-Fluoro-2-bromobenzoic Acid; 2-Bromo-4-fluorobenzoic Acid; Benzoic acid, 2-bromo-4-fluoro-; 4-Fluoro-o-bromobenzoic Acid; o-Bromo-p-fluorobenzoic Acid; 2-Bromo-4-fluorobenzenecarboxylic Acid; 2-Br-4-F-BA
EINECS	213-729-6

Quality Control

Our 2-Bromo-4-Fluorobenzoic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment ensures the material meets the high standards required for research and commercial synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.