Description

3-(Trifluoromethoxy)Benzoic Acid is a high-value fluorinated aromatic building block characterized by its trifluoromethoxy substituent, which imparts unique electronic and steric properties. This compound is essential for introducing lipophilicity and metabolic stability into target molecules, making it a critical intermediate in advanced chemical synthesis. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), particularly in the development of drugs targeting the central nervous system and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethoxy group enhances biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for high-performance displays.
• Polymer Modification: Incorporated as a monomer or additive to create specialty polymers with improved chemical resistance, thermal stability, and surface properties.
• Organic Synthesis & Catalysis: A versatile reagent in cross-coupling reactions and as a ligand precursor in organometallic catalysis for fine chemical production.
• Material Science Research: Utilized in developing advanced organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.

Basic Information

Product Name	3-(Trifluoromethoxy)Benzoic Acid
CAS No.	1014-81-9
Molecular Formula	C8H5F3O3
Molecular Weight	206.12 g/mol
Synonyms	m-(Trifluoromethoxy)benzoic acid; 3-(Trifluoromethoxy)benzoic acid; Benzoic acid, 3-(trifluoromethoxy)-; α,α,α-Trifluoro-m-anisic acid; 3-Carboxy-α,α,α-trifluoroanisole; 3-(Trifluoromethoxy)benzenecarboxylic acid
EINECS	213-806-7

Quality Control

Our 3-(Trifluoromethoxy)Benzoic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	95 - 99 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.