Description

2,3,4,5-Tetrafluorobenzoic Acid is a highly fluorinated aromatic carboxylic acid derivative, serving as a critical building block in advanced chemical synthesis. Its value lies in the unique electronic and steric properties imparted by the tetrafluoro substitution pattern, which is essential for modifying molecular interactions and stability. This compound is primarily needed by the pharmaceutical, agrochemical, and specialty materials industries for applications ranging from active pharmaceutical ingredient (API) development to the creation of novel polymers and liquid crystals.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, where fluorine atoms enhance bioavailability and environmental stability.
• Liquid Crystal Materials: Acts as a core component or side-chain modifier in the synthesis of fluorinated liquid crystals for display technologies.
• Polymer & Resin Modifier: Incorporated into polymer backbones to improve chemical resistance, thermal stability, and surface properties.
• Organic Synthesis Building Block: Employed in coupling reactions (e.g., Suzuki, amidation) to introduce a highly fluorinated benzoic acid moiety into complex molecules.
• Coordination Chemistry Ligand: The carboxylate group can act as a ligand for metal ions in catalyst design and material science.

Basic Information

Product Name	2,3,4,5-Tetrafluorobenzoic Acid
CAS No.	1201-31-6
Molecular Formula	C7H2F4O2
Molecular Weight	194.08 g/mol
Synonyms	Benzoic acid, 2,3,4,5-tetrafluoro-; 2,3,4,5-Tetrafluorobenzenecarboxylic acid; Tetrafluorobenzoic acid (unspecified isomer); Perfluorobenzoic acid (common name); 2,3,4,5-TFBA; TFBzA; EINECS 214-876-7
EINECS	214-876-7

Quality Control

Our 2,3,4,5-Tetrafluorobenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR, to ensure it meets exacting standards for high-purity organic synthesis. Certificates of Analysis (COA) detailing all test results are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	105 - 110 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.