Description

3,4,5,6-Tetrafluorophthalic Acid Dimethyl Ester is a high-value fluorinated aromatic building block, specifically the dimethyl ester derivative of tetrafluorophthalic acid. This compound is prized for its unique electronic and steric properties imparted by the fluorine atoms, making it a critical intermediate in advanced material synthesis. It is primarily sought after by R&D and production teams in the pharmaceutical, agrochemical, and specialty polymer industries for constructing complex molecules and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of fluorinated active pharmaceutical ingredients (APIs), where fluorine substitution can enhance metabolic stability, bioavailability, and binding affinity.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging fluorine's ability to improve lipophilicity and environmental persistence.
• Advanced Polymer & Material Science: Acts as a monomer or cross-linking agent for producing high-performance polymers, such as polyimides and liquid crystal polymers (LCPs), with enhanced thermal stability, chemical resistance, and dielectric properties.
• Organic Electronics: Employed in the fabrication of materials for organic light-emitting diodes (OLEDs) and semiconductors, where fluorinated aromatic systems improve electron transport and device efficiency.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry and material science research, enabling the exploration of structure-activity relationships (SAR) and new material properties.
• Dye & Pigment Intermediate: Utilized in the synthesis of specialized fluorinated dyes and pigments that offer superior lightfastness and unique color properties.

Basic Information

Product Name	3,4,5,6-Tetrafluorophthalic Acid Dimethyl Ester
CAS No.	1024-59-5
Molecular Formula	C10H6F4O4
Molecular Weight	266.15 g/mol
Synonyms	Dimethyl 3,4,5,6-Tetrafluorophthalate; Tetrafluorophthalic Acid Dimethyl Ester; 3,4,5,6-Tetrafluorobenzene-1,2-dicarboxylic Acid Dimethyl Ester; 1,2-Benzenedicarboxylic Acid, 3,4,5,6-Tetrafluoro-, Dimethyl Ester; Phthalic Acid, Tetrafluoro-, Dimethyl Ester; Dimethyl Tetrafluorophthalate; 1024-59-5; NSC 163045
EINECS	213-833-7

Quality Control

Our production of 3,4,5,6-Tetrafluorophthalic Acid Dimethyl Ester adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality system supports development from laboratory to commercial scale, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (typically 15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.