Description

[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-2-[[hydroxy-[hydroxy-[3-hydroxy-2,2-dimethyl-3-[2-[2-[(3S,7S,11R)-3,7,11,15-tetramethylhexadecanoyl]sulfanylethylcarbamoyl]ethylcarbamoyl]propoxy]phosphoryl]oxy-phosphoryl]oxymethyl]oxolan-3-yl]oxyphosphonic acid is a sophisticated, high-purity nucleotide analog derivative designed for advanced research and development. This compound is critical for applications requiring precise biochemical modulation, particularly in the study of enzymatic pathways and cellular signaling. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on developing novel therapeutic agents and diagnostic tools.

Application

• Pharmaceutical Research & Development: As a key intermediate or reference standard in the synthesis and study of novel nucleoside-based therapeutics, including antivirals and anticancer agents.
• Biochemical Assay Development: Used as a substrate, inhibitor, or probe in enzymatic assays to study kinase, polymerase, or other nucleotide-processing enzyme activity.
• Proteomics & Molecular Biology: Employed in the study of protein-nucleic acid interactions, signal transduction pathways, and cellular metabolism research.
• Diagnostic Reagent Manufacturing: Serves as a critical component in the formulation of high-sensitivity diagnostic kits and assays for clinical testing.
• Academic Research: A valuable tool for universities and research institutes conducting fundamental research in medicinal chemistry, biochemistry, and molecular pharmacology.
• Pre-clinical Studies: Utilized in vitro and in vivo studies to investigate drug mechanism of action, pharmacokinetics, and metabolic pathways.

Basic Information

Item	Details
Product Name	[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-2-[[hydroxy-[hydroxy-[3-hydroxy-2,2-dimethyl-3-[2-[2-[(3S,7S,11R)-3,7,11,15-tetramethylhexadecanoyl]sulfanylethylcarbamoyl]ethylcarbamoyl]propoxy]phosphoryl]oxy-phosphoryl]oxymethyl]oxolan-3-yl]oxyphosphonic acid
CAS No.	146622-45-9
Molecular Formula	C41H72N7O16P3S
Molecular Weight	1044.03 g/mol
Synonyms	Adenosine triphosphate derivative; ATP analog; Nucleotide-phytanyl conjugate; Modified nucleoside triphosphate; 2'-Deoxyadenosine-5'-triphosphate analog; Farnesyl-thio-ATP; Isoprenoid-ATP conjugate; Custom nucleotide probe
EINECS	Contact for details

Quality Control

Our production of this high-value nucleotide analog adheres to stringent quality protocols. Each batch is characterized using advanced analytical techniques including HPLC, NMR, and Mass Spectrometry to ensure structural identity and purity. We provide comprehensive Certificates of Analysis (COA) detailing all critical parameters, supporting its use in GLP and research-grade applications. Specifications can be aligned with customer-specific requirements for purity and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider under an inert atmosphere. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.