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2'-Deoxycytidylyl(3'5')-2'-*Deoxyadenosine Ammonium CAS NO 102783-54-0


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CAS No.:102783-54-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2'-Deoxycytidylyl(3'5')-2'-*Deoxyadenosine Ammonium is a high-purity dinucleoside monophosphate ammonium salt, a key building block in oligonucleotide synthesis. This compound is essential for research and development in advanced therapeutic areas, including antisense oligonucleotides and siRNA. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on nucleic acid chemistry and drug discovery.

Application

  • Oligonucleotide Synthesis: A critical phosphoramidite precursor for the solid-phase synthesis of DNA and RNA oligonucleotides.
  • Antisense Drug Development: Used in the research and production of antisense oligonucleotides (ASOs) for therapeutic applications.
  • siRNA and miRNA Research: Serves as a fundamental component in the manufacture of small interfering RNA (siRNA) and microRNA (miRNA) for gene silencing studies.
  • Diagnostic Probe Manufacturing: Employed in the creation of labeled probes for molecular diagnostics and hybridization assays.
  • Biochemical Research: Used as a substrate or intermediate in enzymatic studies of DNA polymerases, ligases, and nucleases.
  • Pharmaceutical Intermediates: Acts as a high-value intermediate in the cGMP-compliant production of novel nucleic acid-based therapeutics.

Basic Information

Product Name 2'-Deoxycytidylyl(3'5')-2'-*Deoxyadenosine Ammonium
CAS No. 102783-54-0
Molecular Formula C19H26N9O10P • xNH3
Molecular Weight Contact for details
Synonyms d(CpA) ammonium salt; 2'-Deoxycytidylyl-(3'→5')-2'-deoxyadenosine ammonium salt; Deoxycytidylyl-(3',5')-deoxyadenosine ammonium; pdCpdA ammonium salt; CpA dimer ammonium salt; Dinucleoside monophosphate d(CpA) ammonium; DNA dimer d(CpA) ammonium; 5'-dCMP-3'-5'-dAMP ammonium salt
EINECS Contact for details

Quality Control

Our 2'-Deoxycytidylyl(3'5')-2'-*Deoxyadenosine Ammonium is manufactured under strict quality systems suitable for research and pharmaceutical intermediate applications. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation. Certificates of Analysis (COA) with detailed chromatographic data are provided to ensure traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to prevent condensation.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC) Conforms to reference standard
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 5.0%
Ammonium Content Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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